Initially synthesized in the 1920s, metformin is a diabetes drug or medication used for treating type 2 diabetes among people who are overweight if not obese.

Unlike many other antidiabetic drugs, metformin has not had the side effect of causing heart problems. In fact, metformin may be able to ease the complications of heart disease or other cardiovascular ailments associated with diabetes.

Also unlike some antidiabetic treatments, metformin is taken orally and not intravenously.

After long neglect as a diabetes drug, metformin has been used in the United States since 1995 and now is considered the most-prescribed diabetes drug on earth.

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